Focus Areas

Bioinstrumentation and Devices

• Jennifer Barton – miniature endoscopes
• Ali Bilgin – MRI and X-ray optimization
• Jean-Marc Fellous – neural implants
• Wolfgang Fink – artificial vision and vision prostheses
• Dongkyun Kang – miniature microscopy devices
• Kaveh Laksari – acceleration-triggered restraint system for brain injury prevention
• David Margolis – in vivo bone strain measurement
• Linda Powers – pathogen sensors and diagnostics
• Marek Romanowski – contrast agent development
• Marvin Slepian – artificial heart
• T. Judith Su – microfabrication of optical instrument
• John Szivek – implantable sensors and radio telemetry
• Nima Toosizadeh – body-worn sensor technology in healthy and geriatric patients
• Urs Utzinger – fiber optic sensing and microscopy
• Russell Witte – ultrasound and electrode technology development
• Jeong-Yeol Yoon – handheld LAMP and PCR systems for pathogen identification

Biomaterials and Tissue Engineering

• Philipp Gutruf – soft inorganic electronic materials and sensors
• Minkyu Kim – artificial protein polymer design, protein and polymer synthesis, (bio)polymer physics and chemistry, synthetic biology, bioconjugation, soft materials, and antimicrobial biomaterials
• David Margolis – bone and cartilage tissue engineering
• Marek Romanowski – nanoparticle and liposome materials for drug delivery
• Marvin Slepian – polymeric biomaterials, biodegradable stents, drug-eluting stents and artificial heart
• John Szivek – 3D-printable materials for implantation with adult stem cells
• Fernando Teran Arce – membrane-mediated cytotoxicity mechanisms
• Jeong-Yeol Yoon – paper-based systems for tissue engineering and organ-on-a-chip applications
• Yitshak Zohar – microfluidic systems for bio-chemical-medical applications

Biomechanics

• Wolfgang Fink – ocular biomechanics
• Samantha Harris – force measurements in cardiac muscle cells to understand mechanisms of cardiac contraction
• Minkyu Kim – molecular biomechanics
• Kaveh Laksari – injury biomechanics
• David Margolis – musculoskeletal tissue biomechanics
• Marvin Slepian – cardiovascular and tubular organ functionality
• John Szivek – load sharing induced by orthopedic implants
• Jil C. Tardiff – mechanical properties of cardiac function in health and disease assessed at the cellular and whole heart levels
• Fernando Teran Arce – biomechanics of cells and membranes
• Nima Toosizadeh – finite element modeling, motion analysis, and assessment of function and cognitive decline in aging population
• Rebecca Vanderpool – cardiovascular hemodynamics
• Russell Witte – ultrasound elasticity and shear wave imaging

Biomedical Imaging and Spectroscopy

• Jennifer Barton – optical coherence tomography and fluorescence spectroscopy
• Ali Bilgin – accelerated MRI and MR parameter mapping, cancer imaging
• Nan-kuei Chen – motion-immune clinical MRI, MRI corrections and improvements
• Wolfgang Fink – Scheimpflug imaging and ray tracing
• Arthur Gmitro – multimodality imaging methods and techniques, confocal microendoscopy
• Dongkyun Kang – in vivo microscopy
• Jen Watson Koevary – cardiovascular imaging
• Kaveh Laksari – neuroimaging in biomechanics
• Linda Powers – sensors and diagnostics using various spectroscopic techniques
• Manoj Saranathan – ultrafast and dynamic MRI, MRI physics and reconstruction with applications to cancer, metabolism, and inflammation
• T. Judith Su – optical resonators and biophotonics
• Jil C. Tardiff – time-resolved and steady-state FRET, differential scanning calorimetry, isothermal calorimetry, stopped-flow fluorescence spectroscopy, regulated in vitro motility, intramyocellular calcium flux
• Fernando Teran Arce – atomic force microscopy
• Ted Trouard – neurological imaging via MRI
• Evan Unger – ultrasound agents
• Urs Utzinger – clinical imaging instrumentation to evaluate gynecological and gastrointestinal cancer
• Russell Witte – hybrid imaging with light, sound and microwaves
• Jeong-Yeol Yoon – smartphone app instant optical scanner

Biomedical Informatics

• Ali Bilgin – data compression
• Jean-Marc Fellous – computational neuroscience, biophysical modeling
• Wolfgang Fink – computer-based classification of visual field data
• Vignesh Subbian – computational medicine, biomedical data science and informatics
• Rebecca Vanderpool – prognostic and diastolic markers of right ventricular function in patients with pulmonary vascular disease

Biosensors

• Philipp Gutruf – soft, bio-integrated, wireless battery free sensor systems
• Samantha Harris – developing force and proximity sensors using FRET.
• Linda Powers – bio-based sensors with biological function as recognition element
• David Margolis – in vivo bone strain and force measurements
• Marvin Slepian – gene sequencing and platelet activation
• T. Judith Su – label-free single molecule detection
• John Szivek – implantable strain and load measurement systems
• Urs Utzinger – biosensors for minimally invasive cancer detection
• Rebecca Vanderpool – pressure transducers for analysis of pulmonary hypertension
• Jeong-Yeol Yoon – smartphone biosensors for medical diagnostics

Cardiovascular Biomedical Engineering

• Jennifer Barton – minimally invasive procedures for the treatment of cardiovascular disease
• Wolfgang Fink – wearable-sensor-based stress management
• Samantha Harris – cardiovascular diseases such as cardiomyopathies and how engineering approaches can provide insights into cardiac physiology
• Minkyu Kim – atherosclerosis
• Jen Watson Koevary – therapeutics and toxicity screening
• Kaveh Laksari – aortic injury due to dynamic bending
• Marek Romanowski – augmented and holographic imaging for surgical guidance
• Marvin Slepian – end-stage congestive heart failure and artificial replacements to bridge support until transplant
• T. Judith Su – micropatterning of extracellular matrix molecules for cellular control
• Jil C. Tardiff – mouse models of genetic cardiomyopathies and the development of small molecule inhibitors to alter disease progression
• Fernando Teran Arce – cell mechanics, cytoskeletal organization and membrane properties in relation to lung and cardiovascular diseases
• Evan Unger – nanodroplets for sonothrombolysis treatment of acute myocardial infarction
• Rebecca Vanderpool – cardiovascular hemodynamics, right ventricular function, pulmonary vascular disease and hypertension
• Russell Witte – acoustoelectric imaging
• Jeong-Yeol Yoon – adhesion between tissue and implanted cardiovascular implanted devices

Nanomedicine

• Minkyu Kim – nanoscale biopolymer physics
• Marek Romanowski – new methods of delivery of therapeutic and diagnostic agents
• Marvin Slepian – local drug delivery and novel therapeutics
• T. Judith Su – microfluidics
• Fernando Teran Arce – nanoscale imaging
• Evan Unger – nanoemulsion for oxygen delivery for clinical trials for stroke and brain cancer
• Yitshak Zohar – organ on a chip

Neuroengineering

• Nan-kuei Chen – human brain connectivity imaging
• Erika Eggers – visual neuroscience, studying the function of retinal neurons with single-cell electrophysiology, confocal imaging, optogenetics and modeling
• Jean-Marc Fellous – in vivo behaving neurophysiology, spatial navigation, memory and emotions circuits
• Wolfgang Fink – human and brain-machine interfaces
• Philipp Gutruf – all optical, wireless and subdermally implanted optogenetic tools
• Kaveh Laksari – traumatic brain injury
• Marek Romanowski – augmented and holographic imaging for surgical guidance
• Manoj Saranathan – MRI of deep brain structures, MRI-guided deep brain stimulation surgery, neuro-image processing
• Vignesh Subbian – traumatic brain injury and intelligent systems and applied machine learning for neurological disorders
• Fernando Teran Arce – Alzheimer’s disease
• Nima Toosizadeh – cognition decline due to aging
• Ted Trouard – development and application of MRI for neuroimaging and drug delivery in neurological disorders
• Urs Utzinger – whole-brain imaging microscopy
• Russell Witte – electrical brain imaging