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Bioscience Research Labs 178
Tsu-Te Judith Su
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Associate Professor of Biomedical Engineering
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Associate Professor of Optical Sciences
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Associate Research Scientist, Chemistry and Biochemistry
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Associate Professor, BIO5 Institute
Judith Su's background is in sensing, imaging, microfabrication and optical instrument building for biological and medical applications. Her research interests are in using imaging, sensing and rheological techniques to reveal basic biological functions at the molecular, cellular and tissue levels. Recently her work has centered on label‐free single molecule detection using microtoroid optical resonators with a focus on basic research, and translational medicine through the development of miniature field portable devices as a tool to detect, understand, control and treat various diseases. She is also developing chemical sensors for environmental monitoring, reducing threats, assisting national defense and enabling clean sport competition.
Degrees
- Ph.D. Biochemistry and Molecular Biophysics
- Caltech, Pasadena, California, United States
- Label-free detection of single biological molecules using microtoroid optical resonators
- M.S. Mechanical Engineering
- MIT, Cambridge, Massachusetts, United States
- B.S. Mechanical Engineering, minor: Literature
- MIT, Cambridge, Massachusetts, United States
Work Experience
- University of Arizona, Tucson, Arizona (2017 - Ongoing)
- University of Arizona, College of Optical Sciences (2015 - 2017)
- Caltech, Division of Biology & Biological Engineering (2014 - 2017)
Interests
Teaching
Biomedical instrumentation, Biophotonics, Biomedical optics
Research
Optical biosensors, Optical microcavities, Whispering gallery modes, Integrated optics, Chemical threat sensing, Microfluidics, Optofluidics, Liquid biopsies, Single molecule dynamics/detection, Bioimaging, Biophotonics, Medical diagnostics, Clean competition, Alzheimer’s diagnostics and prognostics, Environmental monitoring.
Courses
Biophotonics
BME 420 (Spring 2023)
BME 420 (Spring 2020)
BME 420 (Spring 2019)
BME 520 (Spring 2023)
BME 520 (Spring 2020)
BME 520 (Spring 2019)
OPTI 420 (Spring 2023)
OPTI 420 (Spring 2020)
OPTI 420 (Spring 2019)
OPTI 520 (Spring 2023)
OPTI 520 (Spring 2020)
OPTI 520 (Spring 2019)
Directed Research
BME 492 (Spring 2019)
BME 492 (Fall 2018)
Honors Independent Study
OPTI 499H (Fall 2020)
Rsrch Meth Biomed Engr
BME 592 (Fall 2022)
BME 597G (Fall 2019)
Current Subj in Opti Sci
OPTI 595A (Spring 2021)
OPTI 595A (Fall 2020)
Tech Writing & Communication
OPTI 597B (Fall 2023)
OPTI 597B (Fall 2021)
OPTI 597B (Fall 2020)
OPTI 597B (Fall 2019)
OPTI 597B (Fall 2018)
Independent Study
OPTI 599 (Spring 2018)
Biomed Optics+Biphotonic
BME 630 (Fall 2017)
OPTI 630 (Fall 2017)
Biomedical Engr Seminar
BME 696A (Fall 2018)
Bme Student Forum
BME 696C (Spring 2019)
Directed Graduate Research
OPTI 792 (Fall 2023)
OPTI 792 (Fall 2022)
OPTI 792 (Spring 2022)
OPTI 792 (Fall 2021)
OPTI 792 (Spring 2020)
OPTI 792 (Fall 2019)
OPTI 792 (Fall 2018)
Master's Report
OPTI 909 (Spring 2019)
OPTI 909 (Spring 2018)
Thesis
OPTI 910 (Fall 2023)
OPTI 910 (Spring 2021)
OPTI 910 (Fall 2020)
OPTI 910 (Fall 2019)
OPTI 910 (Spring 2019)
OPTI 910 (Fall 2018)
OPTI 910 (Spring 2018)
OPTI 910 (Fall 2017)
Dissertation
BME 920 (Fall 2023)
BME 920 (Spring 2022)
BME 920 (Fall 2021)
OPTI 920 (Spring 2023)
OPTI 920 (Spring 2022)
OPTI 920 (Spring 2021)
OPTI 920 (Spring 2020)
OPTI 920 (Spring 2019)
Selected Publications
Journals/Publications
- , G. C., , A. G., & , J. S. (2022). Optical Frequency Combs in Aqueous and Air Environments at Visible to Near-IR Wavelengths.
- Luu, G. T., Ge, C., Tang, Y., Li, K., Cologna, S. M., Burdette, J. E., Su, J., & Sanchez, L. M. (2022). An integrated approach to protein discovery and detection from complex biofluids. bioRxiv, 2022.01.03.474834.
- Dell'Olio, F., Su, J., Huser, T., Sottile, V., Cortés-Hernández, L. E., & Alix-Panabières, C. (2021). Photonic Technologies for Liquid Biopsies: Recent Advances and Open Research Challenges. Laser & Photonics Reviews, 15(1), 2000255.
- Suebka, S., Nguyen, P., Gin, A., & Su, J. (2021). How Fast It Can Stick: Visualizing Flow Delivery to Microtoroid Biosensors. ACS Sensors, 6(7), 2700-2708.
- Chen, L., Li, C., Liu, Y., Su, J., & Mcleod, E. (2020). Three-Dimensional Simulation of Particle-Induced Mode Splitting in Large Toroidal Microresonators. Sensors, 20(18), 5420. doi:10.3390/s20185420
- Dell'Olio, F., Su, T. J., Huser, T., Sottile, V., Cortés‐Hernández, L. E., & Alix‐Panabières, C. (2020). Photonic technologies for liquid biopsies: recent advances and open research challenges. Laser & Photonics Reviews. doi:https://doi.org/10.1002/lpor.202000255
- Hao, S., & Su, J. (2020). Noise-Induced Limits of Detection in Frequency Locked Optical Microcavities. Journal of Lightwave Technology, 38(22), 6393-6401.
- Chen, L., Li, C., Liu, Y., Su, J., & McLeod, E. (2019). Simulating robust far-field coupling to traveling waves in large three-dimensional nanostructured high-Q microresonators. Photon. Res., 7(9), 967-976.
- Li, C., Chen, L., McLeod, E., & Su, J. (2019). Dark mode plasmonic optical microcavity biochemical sensor. Photon. Res., 7(8), 939-947.
- Mcleod, E., Su, T. J., Liu, Y., Li, C., & Chen, L. (2019). Simulating robust far-field coupling to travelling waves in large three-dimensional nanostructured high-Q microresonators. Photonics Research, 7(9), 967-976.
- Nguyen, P., Zhang, X., & Su, J. (2019). One-Step Controlled Synthesis of Size-Tunable Toroidal Gold Particles for Biochemical Sensing. ACS Applied Nano Materials, 2(12), 7839-7847.
- Ozgur, E., Roberts, K. E., Ozgur, E. O., Gin, A. N., Bankhead, J. R., Wang, Z., & Su, J. (2019). Ultra-sensitive detection of human chorionic gonadotropin using frequency locked microtoroid optical resonators. Analytical Chemistry.
- Su, T. J., Mcleod, E., Chen, L., & Li, C. (2019). Dark mode plasmonic optical microcavity biochemical sensor. Photonics Research, 7(8), 939-947.
- Su, J. (2018). Portable and sensitive air pollution monitoring. Light: Science & Applications, 7(1), 3.
- Su, J. (2017). Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future. Sensors (Basel, Switzerland), 17(3).
Proceedings Publications
- Hao, S., & Su, J. (2021, 2021/3/11). Frequency-locked optical microresonator noise analysis. In Frequency-locked optical microresonator noise analysis, 11635.
- Li, C., Lohrey, T., Nguyen, P., Min, Z., Stoltz, B., & Su, J. (2021, 2021/3/5). Part-per-trillion trace gas detection using frequency-locked whispering gallery mode microtoroids. In Part-per-trillion trace gas detection using frequency-locked whispering gallery mode microtoroids, 11689.
- Su, J. (2021, 2021). Ultra-Sensitive and Selective Detection of DNA and Protein Biomarkers Using Frequency-Locked Microtoroid Optical Resonators. In OSA Technical Digest, SM3O.1.
- Suebka, S., Nguyen, P., Gin, A., & Su, J. (2021, 2021/3/5). Flow visualization of analyte transport to microtoroid optical resonators. In Flow visualization of analyte transport to microtoroid optical resonators, 11637.
- McLeod, E., Su, J., Nguyen, P., & Melzer, J. E. (2020, September). Assembly of Nanophotonic Structures Using Optical Tweezers. In Frontiers in Optics, FTu6B. 5.
- Gin, A., Nguyen, P., Ozgur, E., & Su, J. (2019, 2019). Label-free Ultrasensitive Detection of Amyloid-β Using Lipid-Functionalized Microtoroid Optical Resonators for Early Diagnosis of Alzheimerâs Disease. In OSA Technical Digest, DW1B.5.
- Li, C., Chen, L., McLeod, E., & Su, J. (2019, 2019). Plasmonic Dark Modes for Enhanced Microcavity Biosensing. In The Optical Society, OW2D.2.
- Mcleod, E., Su, T. J., Liu, Y., Li, C., & Chen, L. (2019, July). Simulating Travelling Waves in Large 3D Whispering Gallery Mode Resonators Decorated with Plasmonic Nanoparticles. In Advanced Photonics Congress, IW1A.4.
- Nguyen, P., Gin, A., & Su, J. (2019, 2019). Detection of membrane binding events using microtoroid optical resonators. In OSA Technical Digest, DW2B.1.
- Ozgur, E., Roberts, K. E., Ozgur, E. O., Gin, A. N., Bankhead, J. R., Wang, Z., & Su, J. (2019, 2019). Frequency-locked Optical Whispering Evanescent Resonators for Ultra-Sensitive Doping Detection in Urine. In OSA Technical Digest, DW1B.4.
- Su, J. (2019, 2019). Ultra-Sensitive and Selective Biomolecular Detection Using Frequency-Locked Microtoroid Optical Resonators. In OSA Technical Digest, ITh3A.4.
- Su, T. J., Mcleod, E., Chen, L., & Li, C. (2019, April). Plasmonic Dark Modes for Enhanced Microcavity Biosensing. In Biophotonics Congress: Optics in the Life Sciences, OW2D.2.
- Li, C., Teimourpour, M., Mcleod, E., Su, T. J., Su, T. J., Mcleod, E., Teimourpour, M., & Li, C. (2018, April). Enhanced Whispering Gallery Mode Sensors. In SPIE Defense and Commercial Sensing.
- Su, T. J. (1997, June). On the Fusion of a Line Plume into a Large Scale Vortex Cloud. In American Society of Mechanical Engineers Fluids Engineering Division Summer Meeting, FEDSM-97-170-3672.
Poster Presentations
- Su, T. J. (2021). Identifying and Detecting Diseases Prior to Physical Presentation of Symptoms. 5th Annual Arizona Biomedical Research Center-Flinn Research Conference.
- Su, T. J., Stoltz, B., Melzer, J. E., Li, C., Chen, L., & Mcleod, E. (2019, November). Nanostructuring microtoroid optical chemosensors for mechanically robust and stable sensing. Chemical and Biological Defense Science & Technology Conference. Cincinnati: Defense Threat Reduction Agency (DTRA).
- Roberts, K., Ozgur, E., & Su, T. J. (2017, October). Microtoroid Optical Resonators as a Novel Platform for Selective Drug Detection. Biomedical Engineering Society Annual Fall Meeting. Phoenix, Arizona, USA: Biomedical Engineering Socity.
- Su, T. J. (2014, September). Label-Free Single Exosome Detection Using Frequency Locked Microtoroid Optical Resonators. Exosomes & Single Cell Analysis Summit. Exosomes & Single Cell Analysis Summit, San Diego, CA: Exosomes & Single Cell Analysis Summit.
- Su, T. J., Goldberg, A., Raubitschek, A., Stoltz, B., & Fraser, S. E. (2013, February). Frequency locked microtoroid optical resonators as a non-invasive tumor biopsy alternative. Proceedings of the 57th Biophysical Society Annual Meeting. Proceedings of the 57th Biophysical Society Annual Meeting in Philadephia, PA: Proceedings of the 57th Biophysical Society Annual Meeting.
- Su, T. J., Brau, R. R., Jiang, X., Whitesides, G. M., Lang, M. J., & So, P. (2006, February). Combining Magnetic and Optical Trapping to Quantify Position Dependent Variations in Cellular Rheology. Proceedings of the 50th Biophysical Society Annual Meeting. Proceedings of the 50th Biophysical Society Annual Meeting in Salt Lake City, UT: Proceedings of the 50th Biophysical Society Annual Meeting.
- Su, T. J., Brau, R. R., Jiang, X., Whitesides, G. M., Lang, M. J., & So, P. (2006, July). Combining Magnetic and Optical Trapping to Quantify Position Dependent Variations in Cellular Rheology. Gordon Conference, Lasers in Biology and Medicine. Gordon Conference, Lasers in Biology and Medicine, Meriden, NH: Gordon Conference, Lasers in Biology and Medicine.
- Su, T. J., & So, P. (2005, September). Lithographic Regulation of Cellular Mechanical Properties. Proceedings of the 2005 BMES Annual Fall Meeting. Proceedings of the 2005 BMES Annual Fall Meeting, Baltimore MD: Proceedings of the 2005 BMES Annual Fall Meeting.
- Su, T. J., Jiang, X., Whitesides, G. M., & So, P. (2005, February). Lithographic Regulation of Cellular Migration and Mechanics. Proceedings of the 49th Biophysical Society Annual Meeting. Proceedings of the 49th Biophysical Society Annual Meeting in Long Beach, CA: Proceedings of the 49th Biophysical Society Annual Meeting.
- Su, T. J., & So, P. (2004, February). Lithographic Regulation of Cellular Mechanical Properties. Proceedings of the 48th Biophysical Society Annual Meeting. Proceedings of the 48th Biophysical Society Annual Meeting, Baltimore, MD: Proceedings of the 48th Biophysical Society Annual Meeting.
- Su, T. J., & So, P. (2004, July). Lithographic Regulation of Cellular Mechanical Properties. Gordon Conference, Lasers in Biology and Medicine. Gordon Conference, Lasers in Biology and Medicine, Meriden, NH: Gordon Conference, Lasers in Biology and Medicine.
- Su, T. J., & So, P. (2004, October). Lithographic Regulation of Cellular Mechanical Properties. Proceedings of the 2004 BMES Annual Fall Meeting. Proceedings of the 2004 BMES Annual Fall Meeting in Philadelphia, PA,: Proceedings of the 2004 BMES Annual Fall Meeting.
- Su, T. J., & So, P. (2003, October). Structure and Strength of the Actin Filaments of Micropatterned Cells. Proceedings of the First US National Symposium on Frontiers in Biomechanics Meeting. Proceedings of the First US National Symposium on Frontiers in Biomechanics Meeting, Nashville, TN: Proceedings of the First US National Symposium on Frontiers in Biomechanics Meeting.
- Su, T. J., & So, P. (2003, October). The Actin Structure and Mechanical Behavior of Cells Binding to Extra-Cellular Matrix Adhered to Micropatterned Substrates. Proceedings of the 2003 BMES Annual Fall Meeting. Proceedings of the 2003 BMES Annual Fall Meeting: Proceedings of the 2003 BMES Annual Fall Meeting.
- Su, T. J., Zwieniecki, M., Holbrook, N. M., & So, P. (2003, March). Phloem Transport in Arabidopsis Thalania Seedlings as a Function of Osmotic Stress. Proceedings of the 47th Biophysical Society Annual MeetingBiophysical Society.
Presentations
- Su, T. J. (2021). Detection and prevention of cancer. University of Arizona Cancer Center Convergence 2021University of Arizona Cancer Center.
- Su, T. J. (2021). Early cancer detection using microtoroid optical resonators. University of Arizona Cancer Center Clinical and Translational Oncology Program meetingUniversity of Arizona Cancer Center.
- Su, T. J. (2021). Flow visualization of analyte transport to microtoroid optical resonators. SPIE Photonics West 2021.
- Su, T. J. (2021). Frequency-locked optical microresonator noise analysis. SPIE Photonics West 2021.
- Su, T. J. (2021). Label-free ultra-sensitive molecular detection for chemistry, biology and medicine. CLEO.
- Su, T. J. (2021). Label-free, single-molecule detection using ultra-sensitive optical sensors. Invited Seminar Polytechnic University of Bari, Department of Electrical and Information EngineeringPolytechnic University of Bari, Department of Electrical and Information Engineering.
- Su, T. J. (2021). Medical sensors for disease diagnostics. University of Arizona, College of Engineering Fall 2021 Faculty Lectures Series.
- Su, T. J. (2021). Microtoroid optical sensing technology for biomedical and environmental applications. University of Arizona, Department of Chemistry, Analytical Chemistry Spring Seminar Series.
- Su, T. J. (2021). Microtoroid optical sensing technology for biomedical applications. IEEE Photonics Conference.
- Su, T. J. (2021). Part per trillion trace gas detection using frequency locked whispering gallery mode microtoroid. SPIE Photonics West.
- Su, T. J. (2021). Prevention and detection of breast cancer. University of Arizona, Ginny L. Clements Breast Cancer Research Institute, New Hope for Breast Cancer Research.
- Su, T. J. (2021). Ultra-sensitive and selective detection of DNA & protein biomarkers using frequency-locked microtoroid optical resonators. University of Arizona Health Sciences Tech Talk Tuesdays.
- Gin, A., Nguyen, P., & Su, T. J. (2020, February). Label-free ultrasensitive detection of Amyloid- using microtoroid resonators with lipid surface functionalization. SPIE Photonics West.
- McLeod, E., Su, J., Nguyen, P., & Melzer, J. E. (2020, September). Assembly of Nanophotonic Structures Using Optical Tweezers. Frontiers in Optics. Virtual: Optical Society of America.
- Su, T. J. (2020, February). Ultra-Sensitive and Selective Detection of Protein Biomarkers Using Frequency-Locked Microtoroid Optical Resonators". SPIE Photonics West.
Awards
- National Academy of Inventors Senior Member
- National Academy of Inventors, Spring 2022
- Keynote Speaker, SPIE Photonics West, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications Session
- SPIE, Spring 2022
- Optical Society of America Senior Member
- Optical Society of America, Summer I 2021
- Featured in the 2020 SPIE Women in Optics planner
- SPIE, Winter 2020
- NIH R35 Outstanding Investigator
- NIH, Fall 2020
- Sigma Xi Member
- Sigma Xi, Spring 2020
- Outstanding Paper Award, Light: Science & Applications
- Springer Nature, Summer I 2019
- George H. Davis Travel Fellowship
- University of Arizona, Winter 2018
- American Society of Laser Medicine and Surgery 2019 Dr. Horace Furumoto Innovations Professional Young Investigator Award
- American Society of Laser Medicine and Surgery, Fall 2018
- 2018 Scialog Fellow
- Research Corporation for Science Advancement & the Gordon and Betty Moore Foundation, Spring 2018
- Optical Society of America's Siegman International School Lecturer
- Optical Society of America, Fall 2017
- Top accomplishments in the general field of Optics for 2016
- Optics & Photonics News, Optical Society of America, Winter 2016
- Short Oral Presentation Winner
- GTCbio's Cancer Markers & Liquid Biopsies Conference, Summer I 2015
- NIH Training Grant in Cellular and Molecular Biology,
- National Institutes of Health, Fall 2006
- National Science Foundation Graduate Research Fellowship
- National Science Foundation, Fall 2002
- Pademakar P. Lele Best Undergraduate Thesis Proposal Award
- MIT, Department of Mechanical Engineering, Fall 2001