Ted Trouard
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Professor Emeritus of Biomedical Engineering
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Professor of Medical Imaging
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Professor, BIO5 Institute
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Professor, Evelyn F. McKnight Brain Institute
Dr. Trouard is a leader in development and biomedical application of magnetic resonance imaging, or MRI, technologies. His lab has developed techniques that allow very clear MRI images of stroke that aid in treatment. Dr. Trouard’s imaging techniques also are being used to better diagnose and treat cancer, Alzheimer's disease and Niemann-Pick type C disease. His work also includes using mathematical models that simulate water movement within living tissue to deepen our understanding of what MRI tells us about the body.
Dr. Trouard leads an MRI group at the UA and collaborates with radiologists, pediatricians, neuroscientists, oncologists, geneticists and engineers at University’s Colleges of Engineering, Medicine and Sciences. He also works with scientists throughout the world who are seeking to improve MRI applications for early detection and monitoring of neurological disease and Cancer as well as understand the processes of normal aging of the brain.
Degrees
- Ph.D. Biophysics
- University of Virginia, Charlottessville, Virginia, United States
- B.S. Physics
- California Polytechnic State University, San Luis Obispo, San Luis Obispo, California, United States
Interests
Teaching
Medical Imaging, Introduction to Engineering Design
Research
Magnetic Resonance Imaging (MRI), neuroimaging, focused ultrasound for drug delivery, Alzheimer's Disease, Parkinson's Disease, Niemann-Pick Type C Disease
Courses
Intro to Engineering
ENGR 102 (Fall 2020)
Intro Engr Design
ENGR 102B (Fall 2022)
ENGR 102B (Fall 2021)
ENGR 102B (Fall 2019)
ENGR 102B (Fall 2018)
ENGR 102B (Fall 2016)
Independent Study
BME 299 (Fall 2016)
BME 599 (Spring 2017)
BME 599 (Fall 2016)
Honors Independent Study
BME 299H (Spring 2022)
BME 299H (Spring 2018)
BME 299H (Fall 2017)
Biomedical Imaging
BME 416 (Spring 2019)
BME 416 (Spring 2018)
BME 416 (Spring 2017)
BME 416 (Spring 2016)
Directed Research
BME 492 (Spring 2020)
BME 492 (Fall 2016)
BME 492 (Spring 2016)
Rsrch Meth Biomed Engr
BME 597G (Fall 2019)
BME 597G (Fall 2017)
Directed Graduate Research
OPTI 792 (Spring 2021)
Research
BME 900 (Spring 2017)
BME 900 (Fall 2016)
Thesis
BME 910 (Spring 2021)
BME 910 (Fall 2020)
OPTI 910 (Fall 2022)
OPTI 910 (Spring 2022)
OPTI 910 (Fall 2021)
Dissertation
BME 920 (Spring 2023)
BME 920 (Fall 2022)
BME 920 (Spring 2022)
BME 920 (Fall 2021)
BME 920 (Spring 2021)
BME 920 (Fall 2020)
BME 920 (Spring 2020)
BME 920 (Fall 2019)
BME 920 (Spring 2019)
BME 920 (Fall 2018)
BME 920 (Spring 2018)
BME 920 (Fall 2017)
BME 920 (Spring 2017)
BME 920 (Fall 2016)
BME 920 (Spring 2016)
Selected Publications
Journals/Publications
- Chen, Z., Chen, L., Shirakawa, M., Liu, W., Ortega, D., Chen, J., Balu, N., Trouard, T., Hatsukami, T. S., Zhou, W., & Yuan, C. (2021). Corrigendum to "Intracranial vascular feature changes in time of flight MR angiography in patients undergoing carotid revascularization surgery" [Magn. Reson. Imaging, 75, Jan 2021, 45-50]. Magnetic resonance imaging.
- Chen, Z., Chen, L., Shirakawa, M., Liu, W., Ortega, D., Chen, J., Balu, N., Trouard, T., Hatsukami, T. S., Zhou, W., & Yuan, C. (2021). Intracranial vascular feature changes in time of flight MR angiography in patients undergoing carotid revascularization surgery. Magnetic resonance imaging, 75, 45-50.
- Trouard, T. P., Trouard, T. P., Huentelman, M. J., Huentelman, M. J., Hishaw, G. A., Hishaw, G. A., Grilli, M. D., Grilli, M. D., Etten, E. J., Etten, E. J., Bharadwaj, P. K., Bharadwaj, P. K., Alexander, G. E., & Alexander, G. E. (2021). Influence of regional white matter hyperintensity volume and apolipoprotein E ε4 status on hippocampal volume in healthy older adults.. Hippocampus, 31(5), 469-480. doi:10.1002/hipo.23308
- Alexander, G. E., Lin, L., Yoshimaru, E. S., Bharadwaj, P. K., Bergfield, K. L., Hoang, L. T., Chawla, M. K., Chen, K., Moeller, J. R., Barnes, C. A., & Trouard, T. P. (2020). Age-Related Regional Network Covariance of Magnetic Resonance Imaging Gray Matter in the Rat. Frontiers in aging neuroscience, 12, 267.
- Barnes, C. A., Umapathy, L., Trouard, T. P., Pena, N. M., Gray, D. T., Engle, J. R., Burke, S. N., & Barnes, C. A. (2020). Auditory Processing Deficits Are Selectively Associated with Medial Temporal Lobe Mnemonic Function and White Matter Integrity in Aging Macaques.. Cerebral cortex (New York, N.Y. : 1991), 30(5), 2789-2803. doi:10.1093/cercor/bhz275
- Franchetti, M. K., Bharadwaj, P. K., Nguyen, L. A., Van Etten, E. J., Klimentidis, Y. C., Hishaw, G. A., Trouard, T. P., Raichlen, D. A., & Alexander, G. E. (2020). Interaction of Age and Self-reported Physical Sports Activity on White Matter Hyperintensity Volume in Healthy Older Adults. Frontiers in aging neuroscience, 12, 576025.
- Gray, D. T., De La Peña, N. M., Umapathy, L., Burke, S. N., Engle, J. R., Trouard, T. P., & Barnes, C. A. (2020). Auditory and Visual System White Matter Is Differentially Impacted by Normative Aging in Macaques. The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(46), 8913-8923.
- Kraemer, C., Nisson, P., Wheeler, G., Guzmán Pérez-Carrillo, G. J., Bernstein, A., Hsu, C. H., Bock, D., Trouard, T., & Zhou, W. (2020). Patient risk factors associated with embolic stroke volumes after revascularization. Journal of vascular surgery, 72(6), 2061-2068.
- Lorza, A. M., Ravi, H., Philip, R. C., Galons, J. P., Trouard, T. P., Parra, N. A., Von Hoff, D. D., Read, W. L., Tibes, R., Korn, R. L., & Raghunand, N. (2020). Dose-response assessment by quantitative MRI in a phase 1 clinical study of the anti-cancer vascular disrupting agent crolibulin. Scientific reports, 10(1), 14449.
- Shang, Y., Mishra, A., Wang, T., Wang, Y., Desai, M., Chen, S., Mao, Z., Do, L., Bernstein, A. S., Trouard, T. P., & Brinton, R. D. (2020). Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice. PloS one, 15(1), e0225392.
- Valdez, M. A., Fernandez, E., Matsunaga, T., Erickson, R. P., & Trouard, T. P. (2020). Distribution and Diffusion of Macromolecule Delivery to the Brain via Focused Ultrasound using Magnetic Resonance and Multispectral Fluorescence Imaging. Ultrasound in medicine & biology, 46(1), 122-136.
- Van Etten, E. J., Bharadwaj, P. K., Nguyen, L. A., Hishaw, G. A., Trouard, T. P., & Alexander, G. E. (2020). Right hippocampal volume mediation of subjective memory complaints differs by hypertension status in healthy aging. Neurobiology of aging, 94, 271-280.
- Zhou, W., Nisson, P. L., Chou, Y. H., Zhou, W., Wheeler, G., Trouard, T. P., Nisson, P., Hsu, C. H., Guzman, G., Chou, Y., & Black, J. (2020). Size and Location of Subclinical Microinfarcts Affect Their Cognitive Effects. Journal of Vascular Surgery, 72(1), e19. doi:10.1016/j.jvs.2020.04.043
- Bernstein, A. S., Chen, N. K., & Trouard, T. P. (2019). Bootstrap analysis of diffusion tensor and mean apparent propagator parameters derived from multiband diffusion MRI. Magnetic resonance in medicine, 82(5), 1796-1803.
- Gray, D. T., Umapathy, L., De La Peña, N. M., Burke, S. N., Engle, J. R., Trouard, T. P., & Barnes, C. A. (2019). Auditory Processing Deficits Are Selectively Associated with Medial Temporal Lobe Mnemonic Function and White Matter Integrity in Aging Macaques. Cerebral cortex (New York, N.Y. : 1991).
Proceedings Publications
- Bilgin, A., Do, L., Martin, P. A., Lockhart, E., Bernstein, A. S., Ugonna, C., Dieckhaus, L., Comrie, C., Hutchinson, E. B., Chen, N., Alexander, G. E., Barnes, C. A., & Trouard, T. P. (2021). Accelerating Diffusion Tensor Imaging of the Rat Brain using Deep Learning. In Annual Meeting of the International Society for Magnetic Resonance in Medicine.
- Lindley, M., Bernstein, A. S., McKinnon, A., Ugonna, C., Bruck, D., Johnson, K., Altbach, M. I., Ryan, T. L., Guzman Perez-Carrillo, G., Chen, N., Chou, Y., Trouard, T. P., & Weinkauf, C. C. (2019, Spring). Functional and Microstructural Changes in the Brain After Carotid Endarterectomy. In International Society for Magnetic Resonance in Medicine.
- Terrazas, A., Pyon, W., Zempare, M., Young, K., Dalmendray, A., Do, L., David, B., Bohne, K., Caey, N., Chawla, M., Trouard, T. P., Worley, P., & Barnes, C. (2019, Fall). Effects of NPTX2 knockout on behavior, brain volume by MRI and CA1 hippocampal single unit properties. In Society for Neuroscience.
- Zempare, M., Carey, N., Dalmendray, A., Young, K., Bohne, K., Do, L., Trouard, T. P., Mitchell, K., Chawla, M., Huentelman, M., & Barnes, C. (2019, Fall). Effects of induced hypertension in middle aged CYP1A1-REN2 transgenic rats. In Society for Neuroscience.
- Bernstein, A., Chen, N., & Trouard, T. P. (2018, June). A Bootstrap Analysis of Diffusion MRI Parameters Derived from Simultaneous Multislice Diffusion MRI. In Joint International Society for Magnetic Resonance in Medicine & The European Society for Magnetic Resonance in Medicine and Biology (ISMRM-ESMRMB) Annual Meeting.
- Lindley, M., Bernstein, A., Ugonna, C., Bruck, D., Johnson, K., Altbach, M. I., Ryan, L., Chen, N., Chou, Y., Guzman Perez-Carrillo, G., Trouard, T. P., & Weinkauf, C. C. (2018, June). Impact of Carotid Endarterectomy on Functional Connectivity. In Joint International Society for Magnetic Resonance in Medicine & The European Society for Magnetic Resonance in Medicine and Biology (ISMRM-ESMRMB) Annual Meeting, 5562.
- Trouard, T. P., Chen, N., Bernstein, A., Chang, H. C., Bilgin, A., Bilgin, A., Chang, H. C., Bernstein, A., Chen, N., & Trouard, T. P. (2018, June). A diffusion-matched principal component analysis (DM-PCA) based denoising procedure for high-resolution diffusion-weighted MRI. In Joint International Society for Magnetic Resonance in Medicine & The European Society for Magnetic Resonance in Medicine and Biology (ISMRM-ESMRMB) Annual Meeting.
Poster Presentations
- Bernstein, A., Pokorney, A., Hu, H., Miller, J., Duncan, B. R., & Trouard, T. P. (2017, April). Constrained Spherical Deconvolution Has the Potential to Better Characterize Neuronal Structure in Cerebral Palsy Before and After Therapy.. International Society for Magnetic Resonance in Medicine. Honolulu HI.
- Do, L., Bernstein, A., Alexander, G. E., Barnes, C. A., & Trouard, T. P. (2017, November). Advanced Techniques for Characterizing Rodent Brains with Diffusion MRI.. Society for Neuroscience. Washington DC: SFN.
- Do, L., Do, L., Bharadwaj, P., Bharadwaj, P., Bernstein, A., Bernstein, A., Xiao, J., Xiao, J., Alexander, G. E., Alexander, G. E., Barnes, C. A., Barnes, C. A., Trouard, T. P., & Trouard, T. P. (2017, May). Bias Correction Method Improves Automatic Brain Extraction in Rodent MR Imaging. Arizona Alzheimer's Consortium Scientific MeetingArizona Alzheimer's Consortium.
- Wheeler, G., Do, L., Zhou, W., & Trouard, T. P. (2017, November). Semi-automated Analysis of Microembolic Lesions in Brain Diffusion Weighted MRI. University of Arizona College of Medicine Junior Investigators Forum. Tucson: University of Arizona College of MEdicine.
- Wheeler, G., Do, L., Zhou, W., & Trouard, T. P. (2017, October). Semi-automated Analysis of Microembolic Lesions in Brain Diffusion Weighted MRI. Biomedical Engineering Society Annual Meeting. Phoenix AZ.
Presentations
- Do, L., Bernstein, A., Bharadwaj, P. K., Alexander, G. E., Barnes, C. A., & Trouard, T. P. (2017, November). Advanced Techniques for Characterizing Rodent Brains with Diffusion MRI. Neuroscience 2017. Washington, DC: Society for Neuroscience.
- Do, L., Bernstein, A., Xiao, J., Barnes, C. A., Alexander, G. E., & Trouard, T. P. (2017, October). Advanced Techniques for Characterizing Rodent Brains with Diffusion MRI. Biomedical Engineering Society Meeting. Phoenix AZ: BMES.