Shang Song
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Assistant Professor of Biomedical Engineering
Dr. Song works with organ-on-chip systems and leads investigations on artificial implantable organs through engineering approaches and biomaterials that manipulate cell behavior. Her work has helped applications in neural regeneration, muscle rehabilitation, diabetes treatment, and bone tissue engineering. Her goals are to contribute to the fundamental scientific knowledge at the intersection of biology, engineering, and medicine. Dr. Song joined University of Arizona in 2022 and aspires to advance new diagnostics and therapeutics that better serve the patients in need, help the physicians, as well as improve the public health outcome.
Dr. Song completed her PhD from University of California Berkeley (UC Berkeley) and University of California San Francisco (UCSF), advised by Dr. Shuvo Roy and Dr. Tejal Desai. Her graduate work focused on the development of bioartificial organs and study of interaction between stem cells and biomaterials with engineering and molecular techniques. She received her postdoctoral training on neural repair and neuromuscular recovery techniques through electrical stimulation on stem cell functions under Dr. Paul George and Dr. Thomas Rando at Stanford University. Dr. Song is the recipient of multiple academic awards and fellowships from the National Institute of Health Ruth L. Kirschstein Research Service Awards (NIH NRSA F32), the National Science Foundation Graduate Research Fellowship (NSF GRFP), Rising Stars in Biomedical/Engineering/Health, American Society for Artificial Internal Organs, amongst many others. Her work received further support from the general public and the industry including being named Forbes Magazine 30 Under 30, Baxter’s Young Investigator’s Award 1st Tier winner, Amgen Scholar, and Foundation Capital's Founder’s Program Finalist.
Dr. Song obtained her BS with honors in biomedical engineering from Brown University with support of the Gates Millennium Scholarship. She grew up with her Chinese immigrant parents in the public school system of Guam (US) next to the American military bases. She’s passionate about helping first-generation college students and students from underprivileged backgrounds.
Degrees
- Ph.D. Bioengineering
- Joint Graduate Program from UC Berkeley and UCSF, California
- Silicon Nanopore Membrane (SNM) for islet encapsulation under convective transport to treat Type 1 Diabetes (T1D)
- B.S. Biomedical Engineering (Honors)
- Brown University, Providence, Rhode Island
Work Experience
- Stanford University, Palo Alto, California (2017 - 2021)
- The Sandia National Laboratories (2015 - 2015)
Interests
Teaching
I focus on student-centered teaching with hands-on learning experience. I'm a strong advocate for women, URM, first-gen, and non-traditional students (veterans) in STEM education.
Research
Using engineered biomaterials and cell therapy to develop organ-on-chip systems and artificial implantable organs/devices for diagnostics and therapeutics.
Courses
Stem Cells
BME 487 (Fall 2023)
BME 587 (Fall 2023)
BME 587 (Fall 2022)
Directed Research
BME 492 (Fall 2023)
BME 492 (Fall 2022)
Rsrch Meth Biomed Engr
BME 592 (Fall 2023)
BME 592 (Spring 2023)
BME 592 (Fall 2022)
Biomedical Engr Seminar
BME 696A (Fall 2023)
BME 696A (Fall 2022)
Bme Student Forum
BME 696C (Spring 2023)
Master's Report
BME 909 (Spring 2023)
Thesis
BME 910 (Spring 2023)
BME 910 (Fall 2022)
Selected Publications
Journals/Publications
- Song, S., McConnell, K. W., Amores, D., Levinson, A., Vogel, H., Quarta, M., Rando, T. A., & George, P. M. (2021). Electrical stimulation of human neural stem cells via conductive polymer nerve guides enhances peripheral nerve recovery. Biomaterials, 275, 120982.
- Liu, Y., Li, J., Song, S., Kang, J., Tsao, Y., Chen, S., Mottini, V., McConnell, K., Xu, W., Zheng, Y. Q., Tok, J. B., George, P. M., & Bao, Z. (2020). Morphing electronics enable neuromodulation in growing tissue. Nature biotechnology, 38(9), 1031-1036.
- Suhar, R. A., Marquardt, L. M., Song, S., Buabbas, H., Doulames, V. M., Johansson, P. K., Klett, K. C., Dewi, R. E., Enejder, A. M., Plant, G. W., George, P. M., & Heilshorn, S. C. (2020). Elastin-like Proteins to Support Peripheral Nerve Regeneration in Guidance Conduits. ACS biomaterials science & engineering, 7(9), 4209-4220.
- Song, S., Amores, D., Chen, C., McConnell, K., Oh, B., Poon, A., & George, P. M. (2019). Controlling properties of human neural progenitor cells using 2D and 3D conductive polymer scaffolds. Scientific reports, 9(1), 19565.
- Oh, B., Levinson, A., Lam, V., Song, S., & George, P. (2018). Electrically Conductive Scaffold to Modulate and Deliver Stem Cells. Journal of visualized experiments : JoVE.
- Song, S., & George, P. M. (2017). Conductive polymer scaffolds to improve neural recovery. Neural regeneration research, 12(12), 1976-1978.
- Song, S., Blaha, C., Moses, W., Park, J., Wright, N., Groszek, J., Fissell, W., Vartanian, S., Posselt, A. M., & Roy, S. (2017). An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport. Lab on a chip, 17(10), 1778-1792.
- Song, S., Yeung, R., Park, J., Posselt, A. M., Desai, T. A., Tang, Q., & Roy, S. (2017). Glucose-Stimulated Insulin Response of Silicon Nanopore-Immunoprotected Islets under Convective Transport. ACS biomaterials science & engineering, 3(6), 1051-1061.
- Song, S., & Roy, S. (2016). Progress and challenges in macroencapsulation approaches for type 1 diabetes (T1D) treatment: Cells, biomaterials, and devices. Biotechnology and bioengineering, 113(7), 1381-402.
- Song, S., Faleo, G., Yeung, R., Kant, R., Posselt, A. M., Desai, T. A., Tang, Q., & Roy, S. (2016). Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport. Scientific reports, 6, 23679.
- Song, S., Kim, E. J., Bahney, C. S., Miclau, T., Marcucio, R., & Roy, S. (2015). The synergistic effect of micro-topography and biochemical culture environment to promote angiogenesis and osteogenic differentiation of human mesenchymal stem cells. Acta biomaterialia, 18, 100-11.
- Chen, Y., Song, S., Yan, Z., Fenniri, H., & Webster, T. J. (2011). Self-assembled rosette nanotubes encapsulate and slowly release dexamethasone. International journal of nanomedicine, 6, 1035-44.
- Song, S., Chen, Y., Yan, Z., Fenniri, H., & Webster, T. J. (2011). Self-assembled rosette nanotubes for incorporating hydrophobic drugs in physiological environments. International journal of nanomedicine, 6, 101-7.
- Ward, C. J., Song, S., & Davis, E. W. (2010). Controlled release of tetracycline-HCl from halloysite-polymer composite films. Journal of nanoscience and nanotechnology, 10(10), 6641-9.
Awards
- AR3T Faculty Travel
- Alliance for Regenerative Rehabilitation Research and Training, Fall 2022
- NIH Ruth L. Kirschstein Research Service Awards (NRSA)
- National Institute of Health (NIH), Spring 2019
- Forbes 30 Under 30
- Forbes Magazine, Winter 2016
- Foundation Capital Founder's Program Finalist
- Foundation Capital, Spring 2015
- NSF Graduate Research Fellowship (GRFP)
- National Science Foundation (NSF), Winter 2010
- Gates Millennium Scholar (GMS)
- Bill and Melinda Gates Foundation, Spring 2006