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Arizona Health Sciences Center 4410
Kellen Chen
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Assistant Research Professor of Surgery
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Assistant Research Professor of Biomedical Engineering
Courses
Directed Research
BME 492 (Spring 2023)
Honors Thesis
ECOL 498H (Spring 2024)
Rsrch Meth Biomed Engr
BME 592 (Fall 2023)
BME 592 (Fall 2022)
Master's Report
BME 909 (Spring 2023)
Dissertation
BME 920 (Fall 2024)
Selected Publications
Journals/Publications
- Barrera, J. A., Trotsyuk, A. A., Henn, D., Sivaraj, D., Chen, K., Mittal, S., Mermin-Bunnell, A. M., Larson, M. R., Padmanabhan, J., Kinney, B., Nachbar, J., Sacks, J., Terkonda, S. P., Jeffers, L., & Gurtner, G. C. (2023). Blockchain, Information Security, Control, and Integrity: Who Is in Charge?. Plastic and reconstructive surgery, 152(4), 751e-758e.
- Fischer, K. S., Litmanovich, B., Sivaraj, D., Kussie, H. C., Hahn, W. W., Hostler, A. C., Chen, K., & Gurtner, G. C. (2023). Protocol for the Splinted, Human-like Excisional Wound Model in Mice. Bio-protocol, 13(3), e4606.
- Griffin, M. F., Talbott, H. E., Guardino, N. J., Guo, J. L., Spielman, A. F., Chen, K., Parker, J. B., Mascharak, S., Henn, D., Liang, N., King, M., Cotterell, A. C., Bauer-Rowe, K. E., Abbas, D. B., Diaz Deleon, N. M., Sivaraj, D., Fahy, E. J., Downer, M., Akras, D., , Berry, C., et al. (2023). Piezo inhibition prevents rescues scarring by targeting the adipocyte to fibroblast transition. bioRxiv : the preprint server for biology.
- Henn, D., Trotsyuk, A. A., Barrera, J. A., Sivaraj, D., Chen, K., Mittal, S., Mermin-Bunnell, A. M., Chattopadhyay, A., Larson, M. R., Kinney, B. M., Nachbar, J., TerKonda, S. P., Reddy, S., Jeffers, L., Sacks, J. M., & Gurtner, G. C. (2023). Robotics in Plastic Surgery: It's Here. Plastic and reconstructive surgery, 152(1), 239-249.
- Henn, D., Zhao, D., Sivaraj, D., Trotsyuk, A., Bonham, C. A., Fischer, K. S., Kehl, T., Fehlmann, T., Greco, A. H., Kussie, H. C., Moortgat Illouz, S. E., Padmanabhan, J., Barrera, J. A., Kneser, U., Lenhof, H. P., Januszyk, M., Levi, B., Keller, A., Longaker, M. T., , Chen, K., et al. (2023). Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing. Nature communications, 14(1), 4729.
- Padmanabhan, J., Chen, K., Sivaraj, D., Henn, D., Kuehlmann, B. A., Kussie, H. C., Zhao, E. T., Kahn, A., Bonham, C. A., Dohi, T., Beck, T. C., Trotsyuk, A. A., Stern-Buchbinder, Z. A., Than, P. A., Hosseini, H. S., Barrera, J. A., Magbual, N. J., Leeolou, M. C., Fischer, K. S., , Tigchelaar, S. S., et al. (2023). Allometrically scaling tissue forces drive pathological foreign-body responses to implants via Rac2-activated myeloid cells. Nature biomedical engineering, 7(11), 1419-1436.
- Sivaraj, D., Noishiki, C., Kosaric, N., Kiwanuka, H., Kussie, H. C., Henn, D., Fischer, K. S., Trotsyuk, A. A., Greco, A. H., Kuehlmann, B. A., Quintero, F., Leeolou, M. C., Granoski, M. B., Hostler, A. C., Hahn, W. W., Januszyk, M., Murad, F., Chen, K., & Gurtner, G. C. (2023). Nitric oxide-releasing gel accelerates healing in a diabetic murine splinted excisional wound model. Frontiers in medicine, 10, 1060758.
- Tevlin, R., Griffin, M., Chen, K., Januszyk, M., Guardino, N., Spielman, A., Walters, S., Gold, G. E., Chan, C. K., Gurtner, G. C., Wan, D. C., & Longaker, M. T. (2023). Denervation during mandibular distraction osteogenesis results in impaired bone formation. Scientific reports, 13(1), 2097.
- Abbas, D. B., Lavin, C. V., Fahy, E. J., Griffin, M., Guardino, N., King, M., Chen, K., Lorenz, P. H., Gurtner, G. C., Longaker, M. T., Momeni, A., & Wan, D. C. (2022). Standardizing Dimensionless Cutometer Parameters to Determine Elasticity of Human Skin. Advances in wound care, 11(6), 297-310.
- Borrelli, M. R., Griffin, M., Chen, K., Deleon Diaz, N. M., Adem, S., Mascharak, S., Shen, A. H., Ngaage, L. M., Lewis, N., Longaker, M. T., Gurtner, G., Wan, D. C., & Lorenz, H. P. (2022). Profibrotic Signaling Pathways and Surface Markers Are Up-Regulated in Fibroblasts of Human Striae Distensae and in a Mouse Model System. Plastic and reconstructive surgery, 150(2), 327-338.
- Chen, K., Henn, D., & Gurtner, G. C. (2022). Holy grail of tissue regeneration: Size. BioEssays : news and reviews in molecular, cellular and developmental biology, 44(9), e2200047.
- Chen, K., Henn, D., Januszyk, M., Barrera, J. A., Noishiki, C., Bonham, C. A., Griffin, M., Tevlin, R., Carlomagno, T., Shannon, T., Fehlmann, T., Trotsyuk, A. A., Padmanabhan, J., Sivaraj, D., Perrault, D. P., Zamaleeva, A. I., Mays, C. J., Greco, A. H., Kwon, S. H., , Leeolou, M. C., et al. (2022). Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting. Science Translational Medicine, 14(645). doi:10.1126/scitranslmed.abj9152
- Chen, K., Henn, D., Januszyk, M., Barrera, J. A., Noishiki, C., Bonham, C. A., Griffin, M., Tevlin, R., Carlomagno, T., Shannon, T., Fehlmann, T., Trotsyuk, A. A., Padmanabhan, J., Sivaraj, D., Perrault, D. P., Zamaleeva, A. I., Mays, C. J., Greco, A. H., Kwon, S. H., , Leeolou, M. C., et al. (2022). Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting. Science translational medicine, 14(645), eabj9152.
- Chen, K., Henn, D., Sivaraj, D., Bonham, C. A., Griffin, M., Kussie, H. C., Padmanabhan, J., Trotsyuk, A. A., Wan, D. C., Januszyk, M., Longaker, M. T., & Gurtner, G. C. (2022). Mechanical Strain Drives Myeloid Cell Differentiation Toward Proinflammatory Subpopulations. Advances in wound care, 11(9), 466-478.
- Chen, K., Sivaraj, D., Davitt, M. F., Leeolou, M. C., Henn, D., Steele, S. R., Huskins, S. L., Trotsyuk, A. A., Kussie, H. C., Greco, A. H., Padmanabhan, J., Perrault, D. P., Zamaleeva, A. I., Longaker, M. T., & Gurtner, G. C. (2022). Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 30(3), 397-408.
Poster Presentations
- Chen, K. (2023). Cancer and Lymphatic marker FOXC2 drives wound healing and fibrotic tissue formation.. 9th International Congress on Cancer Metastasis.
Awards
- Career Development Award
- University of Arizona, Summer I 2023
- Dean Louis J. Kettel Award
- University of Arizona, Summer I 2023
- Bernard G. Sarnat, MD, Excellence in Grant Writing Award
- Plastic Surgery Foundation, Spring 2023
- WoundShark Innovation Award
- Wound Healing Society, Spring 2023
- First Place, Young Investigator’s Award
- Wound Healing Society, Spring 2022
- Young Investigator’s Award
- Wound Healing Society, Spring 2022
- First Place Basic Science Research Talk
- Stanford Plastic Surgery Research Day, Fall 2021
- Raven Honor Society
- Raven Honor Society, University of Virginia, Fall 2017