Shang Song

Assistant Professor of Biomedical Engineering
Assistant Professor of Materials Science and Engineering
Member of the Graduate Faculty
Shang Song
520.621.8064
shangsong@arizona.edu

Dr. Shang Song and her team at the University of Arizona deploy novel engineering approaches and biomaterials that can manipulate cellular microenvironment. This facilitates the development of new regenerative medicine and organ-on-chip systems. Her past projects include implantable bioartificial pancreas to treat Type 1 Diabetes, electrically-stimulated stem cell therapy for stroke and peripheral nerve injury recovery, bone tissue engineering, and drug delivery via nano-vehicles. 

Dr. Song completed her PhD from University of California Berkeley (UC Berkeley) and University of California San Francisco (UCSF), advised by Dr. Shuvo Roy, Dr. Qizhi Tang, and Dr. Tejal Desai. Her graduate work focused on the development of bioartificial organs and study of interaction between stem cells and biomaterials with engineering and molecular techniques. She received her postdoctoral training on neural repair and neuromuscular recovery techniques through electrical stimulation on stem cell functions under Dr. Paul George and Dr. Thomas Rando at Stanford University. 

Dr. Song obtained her BS with honors in biomedical engineering from Brown University with support of the Gates Millennium Scholarship. She grew up with her Chinese immigrant parents in the public school system of Guam (US) next to the American military bases. She’s passionate about helping first-generation college students and students from underprivileged backgrounds.

Degrees

  • PhD Bioengineering
    • UC Berkeley and UCSF, California
  • BS Biomedical Engineering (Honors)
    • Brown University, Providence, Rhode Island

Work Experience

  • Stanford University, Palo Alto, California (2017 - 2021)
  • Sandia National Laboratories (2015 - 2015)

Interests

Teaching

I focus on student-centered teaching with hands-on learning experience. I'm a strong advocate for women, URM, first-gen, and non-traditional students (veterans) in STEM education.

Research

Using engineered biomaterials and cell therapy to develop organ-on-chip systems and artificial implantable organs/devices for diagnostics and therapeutics.

Courses

Honors Independent Study

BME 299H (Spring 2024)
 

Stem Cells

BME 487 (Fall 2024)
BME 487 (Fall 2023)
BME 587 (Fall 2024)
BME 587 (Fall 2023)
BME 587 (Fall 2022)
 

Directed Research

BME 492 (Fall 2023)
BME 492 (Fall 2022)
 

Rsrch Meth Biomed Engr

BME 592 (Fall 2023)
BME 592 (Spring 2023)
BME 592 (Fall 2022)
 

Biomedical Engr Seminar

BME 696A (Fall 2024)
BME 696A (Fall 2023)
BME 696A (Fall 2022)
 

Bme Student Forum

BME 696C (Spring 2024)
BME 696C (Spring 2023)
 

Master's Report

BME 909 (Spring 2024)
BME 909 (Spring 2023)
 

Thesis

BME 910 (Spring 2024)
BME 910 (Spring 2023)
BME 910 (Fall 2022)
 

Dissertation

BME 920 (Fall 2024)
BME 920 (Spring 2024)

Selected Publications

Journals/Publications

  • Song, S., McConnell, K. W., Amores, D., Levinson, A., Vogel, H., Quarta, M., Rando, T. A., & George, P. M. (2021). Electrical stimulation of human neural stem cells via conductive polymer nerve guides enhances peripheral nerve recovery. Biomaterials, 275, 120982.
  • Liu, Y., Li, J., Song, S., Kang, J., Tsao, Y., Chen, S., Mottini, V., McConnell, K., Xu, W., Zheng, Y. Q., Tok, J. B., George, P. M., & Bao, Z. (2020). Morphing electronics enable neuromodulation in growing tissue. Nature biotechnology, 38(9), 1031-1036.
  • Suhar, R. A., Marquardt, L. M., Song, S., Buabbas, H., Doulames, V. M., Johansson, P. K., Klett, K. C., Dewi, R. E., Enejder, A. M., Plant, G. W., George, P. M., & Heilshorn, S. C. (2020). Elastin-like Proteins to Support Peripheral Nerve Regeneration in Guidance Conduits. ACS biomaterials science & engineering, 7(9), 4209-4220.
  • Song, S., Amores, D., Chen, C., McConnell, K., Oh, B., Poon, A., & George, P. M. (2019). Controlling properties of human neural progenitor cells using 2D and 3D conductive polymer scaffolds. Scientific reports, 9(1), 19565.
  • Oh, B., Levinson, A., Lam, V., Song, S., & George, P. (2018). Electrically Conductive Scaffold to Modulate and Deliver Stem Cells. Journal of visualized experiments : JoVE.
  • Song, S., & George, P. M. (2017). Conductive polymer scaffolds to improve neural recovery. Neural regeneration research, 12(12), 1976-1978.
  • Song, S., Blaha, C., Moses, W., Park, J., Wright, N., Groszek, J., Fissell, W., Vartanian, S., Posselt, A. M., & Roy, S. (2017). An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport. Lab on a chip, 17(10), 1778-1792.
  • Song, S., Yeung, R., Park, J., Posselt, A. M., Desai, T. A., Tang, Q., & Roy, S. (2017). Glucose-Stimulated Insulin Response of Silicon Nanopore-Immunoprotected Islets under Convective Transport. ACS biomaterials science & engineering, 3(6), 1051-1061.
  • Song, S., & Roy, S. (2016). Progress and challenges in macroencapsulation approaches for type 1 diabetes (T1D) treatment: Cells, biomaterials, and devices. Biotechnology and bioengineering, 113(7), 1381-402.
  • Song, S., Faleo, G., Yeung, R., Kant, R., Posselt, A. M., Desai, T. A., Tang, Q., & Roy, S. (2016). Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport. Scientific reports, 6, 23679.
  • Song, S., Kim, E. J., Bahney, C. S., Miclau, T., Marcucio, R., & Roy, S. (2015). The synergistic effect of micro-topography and biochemical culture environment to promote angiogenesis and osteogenic differentiation of human mesenchymal stem cells. Acta biomaterialia, 18, 100-11.
  • Chen, Y., Song, S., Yan, Z., Fenniri, H., & Webster, T. J. (2011). Self-assembled rosette nanotubes encapsulate and slowly release dexamethasone. International journal of nanomedicine, 6, 1035-44.
  • Song, S., Chen, Y., Yan, Z., Fenniri, H., & Webster, T. J. (2011). Self-assembled rosette nanotubes for incorporating hydrophobic drugs in physiological environments. International journal of nanomedicine, 6, 101-7.
  • Ward, C. J., Song, S., & Davis, E. W. (2010). Controlled release of tetracycline-HCl from halloysite-polymer composite films. Journal of nanoscience and nanotechnology, 10(10), 6641-9.

Awards

  • ORAU 2024 Ralph E. Powe Junior Faculty Enhancement Award
    • Oak Ridge Associated Universities (ORAU), Summer I 2024
  • New Investigator Award
    • Arizona Biomedical Research Centre, Spring 2024
  • Career Development Award
    • American Heart Association, Spring 2024
  • NIH Ruth L. Kirschstein Research Service Awards (NRSA) F32
    • National Institute of Health (NIH), Spring 2019
  • Dean's Postdoctoral Fellowship
    • Stanford University, Fall 2018
  • Forbes 30 Under 30
    • Forbes Magazine, Winter 2016
  • Foundation Capital Founder's Program Finalist
    • Foundation Capital, Spring 2015
  • NSF Graduate Research Fellowship (GRFP)
    • National Science Foundation (NSF), Winter 2010
  • Gates Millennium Scholar (GMS)
    • Bill and Melinda Gates Foundation, Spring 2006