BME Seminar: Leilei Peng
Monday, April 8, 2024 - 12:00 p.m.
Leilei Peng
Associate Professor of Optical Sciences and Biomedical Engineering
University of Arizona
"Synaptic Resolution Stimulation and Imaging of Neural Activity with Two-Photon Bessel Beam Light-Sheet Microscopy"
Keating 103
Zoom link | Password: BearDown
Hosts: Dr. Mario Romero-Ortega and Dr. Shang Song
(Instructor permission required for enrolled students to attend via Zoom)
Persons with a disability may request a reasonable accommodation by contacting the Disability Resource Center at 621-3268 (V/TTY).
Abstract: I will present high speed 3D imaging techniques based on Bessel beam two-photon light-sheet microscopy. These techniques are designed to overcome tissue scattering, penetrate deep into tissue, and perform high speed 3D imaging up to 100 volumes per second with submicron optical resolution. Combining these techniques with two-photon stimulation enables high specialtemporal resolution neural circuit imaging study in brain tissue.
Bio: Leilei Peng received her PhD in physics from Purdue University in 2005 and joined the Wyant College of Optical Sciences at the University of Arizona in 2009. Her lab specializes in inventing and building new fluorescence imaging instruments for biomedical research. Her lab is working in close collaboration bioscience labs to develop advanced techniques for deep tissue imaging, multiplexed fluorescence microscopy and functional volumetric microscopy.