BME Seminar: Hongki Yoo
Monday, October 2, 2023 - 12 p.m.
Hongki Yoo
Associate Professor
Biomedical Optics and Optical Metrology Lab
Dept. of Mechanical Engineering
Korea Advanced Institute of Science and Technology (KAIST)
"Multimodal Endoscopic Optical Imaging for Diagnosing Cardiovascular Disease"
Keating 103
Zoom link | Password: BearDown
Hosts: Dr. Mario Romero-Ortega and Dr. Shang Song
(Instructor permission required for enrolled students to attend via Zoom)
Persons with a disability may request a reasonable accommodation by contacting the Disability Resource Center at 520.621.3268 (V/TTY).
Abstract:
Optical imaging technologies have revolutionized our ability to obtain structural and biochemical data, facilitating high-resolution and precise observations of previously unobservable biological samples. Especially,recent advancements in optical technologies such as lasers and optical fibers have led to the development of noveloptical imaging techniques that are now widely utilized in biological and medical fields. For instance, optical coherence tomography (OCT), an interferometric method for acquiring three-dimensional cross-sections of biological tissue, has successfully been translated into clinical diagnostics, offering microscopic insights intobiological structures. Fluorescence lifetime imaging (FLIm), which measures nanosecond-scale fluorescence decay time, has also emerged as a label-free diagnostic technique, leveraging endogenous auto fluorescence within biological samples. The synergistic combination of OCT and FLIm provides a comprehensive view ofpathological lesions, thereby positioning their combined application as a highly promising method in medicalimaging. In this presentation, I will discuss the technological integration of endoscopic OCT and FLIm into asingle catheter and their applications in diagnosing cardiovascular diseases. I will also explore advancements inimage analysis and image quality improvement through machine learning for coronary imaging.
Bio:
Hongki Yoo is an associate professor in the Department of Mechanical Engineering at the Korea Advanced Institute of Science and Technology (KAIST), Korea. Professor Yoo earned his BS, MS and Ph.D. degrees in mechanical engineering from KAIST. He has worked as a postdoctoral research fellow and an instructor at the Wellman Center for Photomedicine at Harvard Medical School and Massachusetts General Hospital. From 2012 to 2019, Prof. Yoo led the Biomedical Optics and Photomedicine Lab in the Department of Biomedical Engineering at Hanyang University. He joined KAIST in 2019 to establish and lead the Biomedical Optics and Optical Metrology (BOOM) Lab. His research topics include multimodal optical imaging, endoscopic imaging, optical coherence tomography, 3D metrology, diagnostics and therapeutics of cardiovascular disease and machine learning in optical imaging. For more information on Professor Yoo’s research projects, visit his lab’s website at boom.kaist.ac.kr.