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Bioscience Research Labs 332
Kaveh Laksari
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Assistant Professor of Biomedical Engineering
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Assistant Professor of Aerospace and Mechanical Engineering
Degrees
- Ph.D. Mechanical Engineering
- Temple University, Philadelphia, Pennsylvania, United States
- Nonlinear viscoelastic wave propagation in brain tissue.
- M.S. Mechanical Engineering
- Temple University, Philadelphia, Pennsylvania, United States
- Experimental and computational analysis of brain surrogate deformations under linear impact.
- B.S. Mechanical Engineering
- University of Tehran, Tehran, Iran, Islamic Republic of
Interests
Teaching
Biomechanics, numerical methods, continuum mechanics, tissue biomechanics
Research
My research focus is on the field of biomechanics in general and injury biomechanics in particular. I have worked on modeling and preventing traumatic brain injury (TBI) in contact sports, and on modeling arteria wall tissue with a focus on high-rate loadings that could lead to loss of mechanical integrity and eventual dissection. I am also working on using high-performance computing to model patient-specific cerebral hemodynamics in stroke patients.
Courses
Num. Methods in BME
BME 302 (Spring 2019)
Biomechanical Engr
AME 466 (Fall 2020)
AME 466 (Fall 2018)
AME 466 (Fall 2017)
AME 566 (Fall 2020)
AME 566 (Fall 2019)
AME 566 (Fall 2018)
AME 566 (Fall 2017)
BME 466 (Fall 2020)
BME 466 (Fall 2019)
BME 466 (Fall 2018)
BME 466 (Fall 2017)
BME 566 (Fall 2020)
BME 566 (Fall 2019)
BME 566 (Fall 2018)
BME 566 (Fall 2017)
Directed Research
BME 492 (Spring 2021)
BME 492 (Fall 2020)
BME 492 (Fall 2019)
BME 492 (Spring 2019)
BME 492 (Fall 2018)
BME 492 (Spring 2018)
Rsrch Meth Biomed Engr
BME 592 (Fall 2020)
BME 597G (Fall 2019)
BME 597G (Fall 2018)
BME 597G (Fall 2017)
Independent Study
BME 599 (Spring 2019)
Research
BME 900 (Fall 2020)
BME 900 (Spring 2020)
BME 900 (Fall 2019)
Thesis
AME 910 (Fall 2020)
AME 910 (Spring 2020)
BME 910 (Spring 2021)
Dissertation
BME 920 (Spring 2021)
BME 920 (Fall 2020)
BME 920 (Spring 2020)
BME 920 (Fall 2019)
Selected Publications
Journals/Publications
- Agah, M. R., Laksari, K., & Darvish, K. (2021). Hyperelastic Behavior of Porcine Aorta under Sub-Failure Inflation Loading.
- Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2021). Mechanical Properties of Brain White Matter under Repetitive Loading Condition: Introducing a Mechanical Damage Function.
- Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2021). Mind the gap: A mechanobiological hypothesis for the role of gap junctions in the mechanical properties of injured brain tissue. Journal of the mechanical behavior of biomedical materials, 115, 104240.
- Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2021). Visco-hyperelastic Properties of White and Gray Matters under Tension: an Ex-vivo Study.
- Laksari, K., & Darvish, K. (2021). Nonlinear Shock Wave Propagation in Soft Tissues as a Mechanism of Injury.
- Ozkaya, E., Fabris, G., Macruz, F., Suar, Z. M., Abderezaei, J., Su, B., Laksari, K., Wu, L., Camarillo, D. B., Pauly, K. B., & others, . (2021). Viscoelasticity of children and adolescent brains through MR elastography. Journal of the Mechanical Behavior of Biomedical Materials, 115, 104229.
- Arru'e, P., Toosizadeh, N., Babaee, H., & Laksari, K. (2020). Low-Rank Representation of Head Impact Kinematics: A Data-Driven Emulator. Frontiers in Bioengineering and Biotechnology, 8, 1049.
- Arrue, P., Toosizadeh, N., Babaee, H., & Laksari, K. (2020). Low-rank representation of head impact kinematics: A data-driven emulator. arXiv preprint arXiv:2004.12979.
- Deshpande, A., Jamilpour, N., Jiang, B., Kidwell, C., Wintermark, M., & Laksari, K. (2020). Automatic Segmentation, Feature Extraction and Comparison of Healthy and Stroke Cerebral Vasculature. arXiv preprint arXiv:2002.11208.
- Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2020). A knowledge map analysis of brain biomechanics: Current evidence and future directions. Clinical Biomechanics, 75, 105000.
- Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2020). Structural Anisotropy vs. Mechanical Anisotropy: The Contribution of Axonal Fibers to the Material Properties of Brain White Matter. Annals of Biomedical Engineering, 1--9.
- Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2020). Tension strain-softening and compression strain-stiffening behavior of brain white matter. Annals of Biomedical Engineering, 1--11.
- Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2020). The importance of axonal directions in the brainstem injury during neurosurgical interventions. Injury.
- Kumar, D. P., Wendel, C., Mohler, J., Laksari, K., & Toosizadeh, N. (2020). Between-day repeatability of sensor-based in-home gait assessment among older adults: assessing the effect of frailty. Aging clinical and experimental research, 1--9.
- Laksari, K., Fanton, M., Wu, L. C., Nguyen, T. H., Kurt, M., Giordano, C., Kelly, E., O'Keeffe, E., Wallace, E., Doherty, C., & others, . (2020). Multi-directional dynamic model for traumatic brain injury detection. Journal of neurotrauma, 37(7), 982--993.
Proceedings Publications
- Agah, M. R., Laksari, K., & Darvish, K. (2012, June). Hyperelastic Behavior of Porcine Aorta under Sub-Failure Inflation Loading. In Summer Bioengineering Conference.
- Laksari, K., Darvish, K., & Sadeghipour, K. (2012, May). Nonlinear Shock Wave Propagation in Soft Tissues as a Mechanism of Injury. In Injury Biomechanics Symposium.
- Laksari, K., Wu, L., Nguyen, T., Kurt, M., Fanton, M., Ruan, J., Barbat, S., & Camarillo, D. (2017). MULTI-DIRECTIONAL DYNAMIC INJURY METRIC FOR MILD BRAIN TRAUMA DETECTION. In JOURNAL OF NEUROTRAUMA, 34.
- Assari, S., Laksari, K., Barbe, M., & Darvish, K. (2013). Cerebral blood pressure rise during blast exposure in a rat model of blast-induced traumatic brain injury. In ASME 2013 International Mechanical Engineering Congress and Exposition.
- Assari, S., Laksari, K., Barbe, M., & Darvish, K. (2013). Cerebral blood pressure rise during blast exposure in a rat model of blast-induced traumatic brain injury. In From the ASME 2013 International Mechanical Engineering Congress and Exposition, 3.
- Kermani, G., Laksari, K., & Darvish, K. (2013). Biomechanical Properties of Human Aorta from Dynamic Biaxial Loading. In Bioengineering Conference (NEBEC), 2013 39th Annual Northeast.
- Laksari, K., Assari, S., & Darvish, K. (2013). COMPUTATIONAL COMPARISON OF SHOCK WAVE PROPOAGATION IN EXPLOSIVE BLAST AND SHOCK TUBE EXPERIMENTS. In ASME 2013 International Mechanical Engineering Congress and Exposition.
- Laksari, K., Assari, S., & Darvish, K. (2013). Computational Comparison of Shock Wave Propagation in Explosive Blast and Shock Tube Experiments. In ASME International Mechanical Engineering Congress and Exposition, 56215.
- Laksari, K., Assari, S., & Darvish, K. (2013). Computational Simulation of Shock Tube and the Effect of Shock Thickness on Strain-Rates. In Bioengineering Conference (NEBEC), 2013 39th Annual Northeast.
- Agah, M. R., Laksari, K., & Darvish, K. (2012). Investigating the hyperelasticity of porcine aorta under sub-failure loading. In Bioengineering Conference (NEBEC), 2012 38th Annual Northeast.
- Agah, M. R., Laksari, K., Darvish, K., & Rachev, A. (2012). Buckling of Porcine Aorta under Static and Dynamic Loading. In American Society of Mechanical Engineering Summer Bioengineering Conference.
- Laksari, K., Agah, M. R., & Darvish, K. (2012). Hyperelastic Behavior of Porcine Aorta in Sub-Injury Pressures. In American Society of Mechanical Engineering Summer Bioengineering Conference.
- Laksari, K., Agah, M. R., Rachev, A., & Darvish, K. (2012). Investigating the effects of dynamic and static loading on the stability of porcine aorta. In Bioengineering Conference (NEBEC), 2012 38th Annual Northeast.
- Shafieian, M., Laksari, K., Darvish, K., & Crandall, J. (2012). Development of a constitutive model for brain tissue under multiaxial loading. In Proceedings of the 2012 International IRCOBI Conference on the Biomechanics of Injury.
- Laksari, K., Darvish, K., & Sadeghipour, K. (2011). Shock Wave as a Mechanism of Injury in Soft Tissues. In ASME 2011 Summer Bioengineering Conference.
Others
- Kuo, C., Wu, L. C., Laksari, K., & Camarillo, D. B. (2017). Oral appliance for measuring head motions by isolating sensors from jaw perturbance.
- Hernandez, F., Laksari, K., & Camarillo, D. B. (2015). System for redirecting head impact force.
- Laksari, K. (2013). Nonlinear viscoelastic wave propagation in brain tissue.
- Laksari, K. (2009). Experimental and Computational Analysis of Brain Surrogate Material Under Linear Impact.